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Impact Profiles

Welcome to the Impact Profiles page.

Researchers funded by ACCEL are producing significant and innovative contributions across clinical and translation domains that advance knowledge and support the translation of research into practice.

The impact profiles found on this page illustrate these contributions, summarize research progress, and highlight their relevance for communities, practitioners, and policymakers. Click on the titles to access the full impact profile.


 

    Food Access, Nutrition Assistance, and Addressing Stigma in the Face of Food Insecurity

    Food insecurity affects approximately 1 in 7 U.S. households, reflecting persistent inequities in access to affordable, nutritious food. Beyond income constraints, structural factors – including retail food environments, pricing strategies, and nutrition policy implementation – shape what foods are available and promoted in communities, often reinforcing disparities in diet quality and health.

    Clinical & medical benefits
    Community & public health benefits
    Policy & legislative benefits

    Investigating Sleep Health Disparities in Socioeconomically Disadvantaged Families

    Approximately 90% of children obtain less sleep than recommended, and poor sleep health is linked to impaired cognitive, emotional, and physical development and increased risk of long-term disease. Many families, particularly those experiencing socioeconomic or environmental challenges, face barriers to establishing safe and consistent sleep routines. Understanding these barriers is essential to inform strategies that support early childhood healthy sleep habits.

    Clinical & medical benefits
    Community & public health benefits
    Policy & legislative benefits

    Sickle Cell Retinopathy: Retinal imaging to improve detection and monitoring of sickle cell disease progression in children

    Sickle cell retinopathy develops due to blockages in blood vessels in the retina, leading to abnormal blood vessel growth and retinal thinning. It is the most common cause of vision impairment in individuals with sickle cell disease. Sickle cell disease has a global incidence rate of 515,000 neonates, with approximately 100,000 individuals affected in the United States.

    Clinical & medical benefits
    Policy & legislative benefits
    Economic benefits

    Congenital heart disease: Family-based psychosocial interventions

    Congenital heart defects (CHD) are widely recognized as the most common birth defect in the United States. Up to 30–50% of individuals with CHD experience some form of neurodevelopmental or psychological difficulty, such as learning challenges, attention deficits, or anxiety.

    Clinical & medical benefits
    Community & public health benefits
    Policy & legislative benefits

    Early detection and interventions for infants and children with movement delays

    Movement delays stem from a variety of causes, including brain injuries occurring before, during, or soon after birth. In the U.S., 7 infants per 1,000 births experience such brain injuries, placing them at high risk for lifelong motor and cognitive impairments. Most children with motor delays, such as children with cerebral palsy, are not diagnosed in the first two years of life, thus missing a critical window to implement early, effective interventions.

    Clinical & medical benefits
    Community & public health benefits
    Policy & legislative benefits
    Economic benefits

    Cancer Prevention and Control

    Over 2 million new cancer cases are diagnosed each year in the United States. In Delaware, the incidence and mortality rates due to cancer surpass those of the U.S., with over 457 per 100,000 individuals diagnosed and 156 per 100,000 succumbing to cancer each year. Black and Hispanic populations having lower screening rates, decreased access to care, and more advanced cancer at diagnosis as compared to the White population.

    Clinical & medical benefits
    Community & public health benefits
    Policy & legislative benefits
    Economic benefits

    Firearm Violence Prevention and Intervention

    Firearm violence is a major public health problem in the United States, injuring more than 68,000 individuals and killing over 20,000 individuals annually. Firearm homicides are the leading cause of death for persons 1-19 years of age. In addition, males are more likely to be victims of firearm homicides than females. In 2022, the firearm homicide rate was 24 times higher among Black males ages 15-34 compared to same age white males.

    Clinical & medical benefits
    Community & public health benefits
    Policy & legislative benefits
    Economic benefits