Shovel-Ready Pilot Grants Program (ShoRe PGP)
Goals & Background
Many investigators submit proposals and receive good scores but yet are not funded due to today’s competitive climate. To aid such investigators transition their good proposals into fundable ones, the ACCEL Program has created this Shovel-Ready Grant Program (SHoRe Grants). These awards are for investigators who already have submitted research grant applications (NIH, PCORI, VA, NSF, etc.) and have received summary statements, but need funds to collect additional data to strengthen their resubmission and address reviewer concerns.
The SHoRe RFP solicits applications for projects that will be completed within six months and must result in a resubmitted research grant application.
The technical scope of the research plan should be related to clinical and translational research (see Rubio et al., 2010). Areas of high importance to the DE-CTR ACCEL program include
- Preventive Care
- Behavioral and Mental Health
Other areas of clinical and translational research will be considered. Use of one or more of the research cores at the ACCEL institutions is encouraged, but not mandatory. Information about these cores can be found on the ACCEL website.
The proposal format (11 point, Arial) is similar to that for an NIH R03 proposal, except for the length of the research description section. Proposals should be submitted at https://apps.de-ctr.org/dash/apps/proposal/pilot/ using PHS 398 forms. Instructions can be found here. Each proposal should include the following sections (sections L is only required for junior investigators):
- NIH face page (download here)
- NIH Page 2&3: Summary, Relevance, Project/Performance Sites, Senior/Key Personnel (download here)
- Budget using NIH forms Page 4, including budget justification on Page 5 (download hereand here)
- Biographical Sketch(es) of PI and Key Personnel including the primary mentor, other members of the mentoring team, and collaborators who would play a significant role in accomplishing the goals of the proposal (NEW form)
- Summary statement from previous research grant.
- Research Strategy (See below—using NIH continuation forms—download here)
- Success from Prior IDeA Awards: PIs who have led a project supported by CTR, INBRE, COBRE or DHSA grants should include a short section (1 page maximum) outlining the progress on that prior work, including their success in leveraging that research into independent external support and explaining why further support is necessary. (use NIH continuation forms)
- References (use NIH continuation forms)
- NIH Human subjects (download here) and planned enrollment forms (here), if applicable
- Vertebrate animals justification and protection (download here), if applicable
- A letter of Support from the PI’s Department Head/Chair
- If the project is led by a new investigator (NIH definition), the application must include a letter of support from the primary mentor detailing previous experience, the candidate’s potential, the existing mentoring or working relationship (if any), and specifics as to how the mentor will interact with the candidate during the funding period (mentoring agreement)
- Applications may include an introduction (one page maximum) that summarizes substantial changes to the application and/or responds to issues and criticisms raised in a prior review. Use NIH continuation forms—download here.
- Community engagement form (here) if applicable.
The proposal need not be routed through the institutional research offices for institutional signatures (unless required), but upon submission may be forwarded to the PI’s appropriate institutional office for budget and effort verification.
Pre-Submission Assistance and Feedback
Applicants are encouraged to consult with the ACCEL Biostatistics, Epidemiology & Research Design (BERD) Core to review their statistical and methodological approach prior to submission: https://www.de-ctr.org/dash/apps/biostat/. Be sure to indicate that the request is linked to a Clinical and Translational Pilot Grant submission.
Also, the BERD core has established mechanisms to obtain access to Medicaid and Medicare claims data. Please contact Claudine Jurkovitz firstname.lastname@example.org for more information.
Proposals led by new investigators (see NIH definition here) will be required to work with our Professional Development Core (PD-Core) to submit detailed mentoring plans (from the mentors) and Individual Development Plans (from the PIs) prior to receiving funds. The Mentoring Plan and IDP are not required as part of the original submission process but applicants are encouraged to use the tools to help in planning the submission (see https://apps.de-ctr.org/dash/apps/medcore/).
The PD Core offers a Flight School to help investigators get ready to submit a Pilot grant to the Delaware CTR ACCEL.
a) At the first session (January 17, 12:00-1:00), submission requirements are reviewed and research ideas for each pilot proposal are discussed. Additional resources needed by investigators are identified.
b) At the second session (February 13, 11:30-1:30), specific aims are reviewed and discussed, and the other components of the proposal are reviewed. The draft specific aims are due to Erin.Riegel@nemours.org by noon on 2/6/2020.
You can attend in person or connect via phone/computer. Contact Erin.Riegel@nemours.org for directions or access information.
Applicants are strongly recommended to engage with our Community Engagement and Outreach (CEO) Core as part of the pre-submission process: https://www.de-ctr.org/redcap/surveys/?s=PF7989REXL for assistance with framing the relevance and potential impact of projects and for connection to community partners where appropriate. In addition, applicants for community engaged projects must complete or show competence in ACE curriculum (insert link) within 6 months of start date.
The Research Strategy part of the proposal (section F above) should be organized in four sections to describe the (1) Specific Aims of the work, (2) Significance, (3) Innovation, and (4) Approach. Together, these four sections should be a maximum of four pages in length. The focus of the proposal should be on what will be done in the six month time period to address the reviewers’ comments and strengthen the original proposal to improve the score.
Within the Approach section, a statistical analysis subsection is required. If applicable, within the Approach section applicants should also discuss the potential for community engagement. Information about the ACCEL Cores can be found on the ACCEL website.
Human subjects Institutional Review Board (IRB) or Vertebrate animal IACUC approval is not required at the time of SHoRe project submission. However, if applicable, such approval is required before the selected projects are sent to the NIH for federal approval on June 24. If a project is selected for funding by the ACCEL External Advisory Committee but does not have IRB/IACUC approval by June 24, funding of the proposal may be deferred.
Investigators who will be doing work at hospitals may need to obtain credentials. Such investigators are encouraged to begin that process well in advance of the start date of the grant as the process can take several months.
Each proposal must be submitted by one investigator from one of the ACCEL partner institutions (i.e., University of Delaware, Nemours, Christiana Care Health System, Delaware State University and the Medical University of South Carolina). Proposals that include investigators from multiple partner institutions are especially encouraged and are given priority. Note: multiple PI applications are not allowed and only a single PI will be recognized.
Leaders of SHoRe projects must hold a faculty appointment or equivalent at the time the pilot award commences. These are individuals who can independently apply for Federal or non-Federal investigator-initiated peer-reviewed Research Project Grants (RPG). Individuals holding postdoctoral fellowships or other positions that lack independent status are not eligible to lead pilot projects.
The Project lead for SHoRe projects may not concurrently have research funding from other IDeA Program award mechanisms (e.g. INBRE, COBRE, CTR).
SHoRe project funding may not overlap with ongoing funded projects.
Mentors: Proposals led by junior or “new” investigators (see NIH definition here) must identify a suitable mentor, and include the proposed mentor’s Letter of Support demonstrating his willingness to participate and support the applicant and project. Mentors with prior experience as PI on an NIH funded grant are preferred.
Proposals should be submitted electronically using the ACCEL website office by noon on May 1, 2020. Note that all investigators on the proposal must have user accounts on the ACCEL website prior to submission. Contacting the other cores for support (i.e., Epidemiology/Biostatistics and Community Engagement—see Pre-Submission section above) must be done at least two weeks before the submission date.
Up to $20,000 (direct costs) may be requested. A typical SHoRe grant will support clinical research coordinators, postdoctoral fellows, or graduate students, as well as appropriate amounts for supplies, travel, etc. PI salary is discouraged as faculty release time for this work is expected to be provided as an institutional commitment; the anticipated effort should be indicated in the budget. A budget period of up six months may be requested. Investigators should plan for funding to begin on or soon after August 15, 2020. PIs should work with institutional ACCEL research officers prior to submission:
Each ACCEL SHoRe Project will be evaluated via a three-step process. In the first step, proposals will be evaluated based on scientific merit as is done in NIH study sections. Proposals will be given five scores based on significance, investigators, innovation, approach, and environment (especially as it pertains to the type of research being proposed in relation to established Cores). They will then be given an overall impact score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, as well is its chance of being developed into a full NIH proposal with a high likelihood of success. Scores are on a 1 (exceptional) through 9 (poor) scale, following the standard NIH guidelines for reviews of individual (R-type) research grants. Proposals will be given another score based on how the scope of work and investigator’s status correspond to the priorities of the ACCEL Program. Questions to be addressed include: Has the investigator received previous funding? If so, has it been well used? Is the research translational?
In the second step, the ACCEL Executive Committee will then determine which grants to recommend for funding based on the priority scores and the ACCEL mission. Additional scores will be provided by our CEO Core to determine if projects are addressing the health outcomes of Delawareans and by BERD to assess experimental design. In the third step, final approval for funding will be made by the External Advisory Committee, albeit with NIH approval.
Preference will be given as follows:
- Proposals from multiple partner institutions are given priority over those from single institutions.
- While all projects must be translational, at least half of the projects that will be funded must be clinical in nature (i.e., although not a requirement, clinical projects are especially welcome).
- Projects generated from ACCEL sponsored research planning retreats will be given priority.
Awardees are required to attend the annual ACCEL Research Conference and to present their work at the annual (national or regional) NIH IDeA Conference. They are required to cite the ACCEL grant (NIH U54 GM104941) on all publications and to submit quarterly progress reports. Also, for “new” investigators, active participation in the mentoring process is required for both mentors and mentees, which includes completion of mentor reports. Award recipients must keep ACCEL profiles up to date (at least twice per year) and respond to ACCEL surveys. They will be responsible for reporting on any outcomes at the end of award and up to three years post award end.