Meta Data Analysis
Thursday October 2, 2025 from 12:00-1:00pm
Virtual Teams Presentation
Meta-Data Analysis is a powerful statistical method that synthesizes findings across multiple studies to derive more precise and generalizable estimates of treatment effects. In addition to pooling odds ratios to evaluate categorical outcomes, this method also enables estimation of continuous outcomes—such as mean changes and their confidence intervals—across diverse study populations. Meta-analysis increases statistical power, enhances clinical interpretability, and allows quantification of heterogeneity using metrics like I² and τ². This talk provides a comprehensive overview of meta-analytic techniques, including data preparation, calculation of pooled estimates for both binary and continuous outcomes, exploration of subgroup effects, and interpretation of results using forest plots and summary tables. Drawing from recent real-world comparative effectiveness studies in medicine and public health, this session will illustrate how incorporating newly available studies can update pooled evidence, and how summary findings can directly inform clinical decision-making and health policy evaluation.
Meet the Speaker
Zugui Zhang, PhD
Director of Biostatistics
Christiana Care Health Systems
Dr. Zugui Zhang is director of biostatistics at iREACH, ChristianaCare and Fellow of American Heart Association. He received an MS in statistics from Arizona State University and his PhD in biostatistics from the University of Iowa. He joined ChristianaCare in 2007 and has been Director of Biostatistics since 2017. He holds appointments as Affiliated Professor of Biostatistics at the University of Delaware and Thomas Jefferson University. He has worked extensively on large, international, multi-center, randomized clinical trials and observational studies.
Microsoft Teams
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Meeting ID: 260 254 371 463
Passcode: 5tL3rC9q
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+1 302-483-7154,,560603931# United States, Wilmington
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Phone conference ID: 560 603 931#
To receive instructions on obtaining (1) CME credit for attendance, please RSVP to Debra.Reese@ChristianaCare.org.
Work supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant number U54-GM104941 (PI:Hicks) and the State of Delaware.