Tech Talk: Introduction to Mediation Analysis

  • November 3, 2022 from 12:00-1:00pm
  • Virtual presentation via BlueJeans ( | Meeting ID 361095905
  • Please RSVP by emailing Debra Reese. Please include your full name, email address, and institution/organization.
  • This activity has been approved for AMA PRA Category 1 Credit. We will provide instructions on obtaining CME credit for attendance.

“Introduction to Mediation Analysis”

Mediation is the process by which one variable transmits an effect onto another through one or more mediating variables. Mediation analysis tests a hypothetical causal chain where one variable X affects a mediator variable M and, in turn, that the mediator variable M affects a third (often outcome) variable Y. Mediators describe the how or why of a (typically well-established) relationship between two other variables and are sometimes called intermediary variables since they often describe the process through which an effect occurs, which is called an indirect effect.  This talk will explain what a mediation analysis is, show how to work with data for mediation analysis, run the necessary statistical procedures and test, and address how to interpret the results from mediation analysis.

Meet the Speaker

Zugui Zhang, PhD, is director of biostatistics at iREACH, ChristianaCare and Fellow of American Heart Association. He received an MS in statistics from Arizona State University and his PhD in biostatistics from the University of Iowa. He joined ChristianaCare in 2007 and has been Director of Biostatistics since 2017. He holds appointments as Affiliated Professor of Biostatistics at the University of Delaware and Thomas Jefferson University. He has worked extensively on large, international, multi-center, randomized clinical trials and observational studies.

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